Searchable abstracts of presentations at key conferences in endocrinology

ea0022oc6.5 | Bone | ECE2010

The ratio of PTH as measured by third and second generation assays as a marker for parathyroid carcinoma

Cavalier Etienne , Daly Adrian F , Betea Daniela , Delanaye Pierre , Stubbs Phil , Bradwell Athur R , Chapelle Jean-Paul , Beckers Albert

Background: Parathyroid carcinoma (PCa) is a rare disease that can be difficult to differentiate initially from benign parathyroid adenoma. PCa over-secrete the amino form of parathyroid hormone (PTH), which is recognized by 3rd generation but not by 2nd generation (‘intact’) PTH assays. In normal individuals, the 3rd generation/2nd generation PTH ratio should always be <1.Material and methods: We studied the utility of the 3rd generation/2...